Test for anti-sperm antibodies
Sperm do not enter the bloodstream and, under normal conditions, the male reproductive system does not contain anti-sperm antibodies. However, when the blood-testis barrier is breached, the immune system can detect mature spermatozoa as antigenic and form anti-sperm antibodies that cause sub-fertility or infertility. Anti-sperm antibodies belong to two immunological classes: IgA and IgG antibodies. IgA anti-sperm antibodies are clinically associated with immunological infertility, so screening can help assess male fertility.
The SpermMar IgA test is a semi-quantitative, non-automated diagnostic kit for the detection of IgA class anti-sperm antibodies on spermatozoa in human semen. It is a rapid, easy-to-use microscopic test.
The SpermMar IgA test can be performed on fresh, untreated human semen, provided it contains motile spermatozoa. The SpermMar IgA test can be used as an aid in the diagnosis and management of male infertility.
The SpermMar IgA test has a shelf life of 12 months from the date of production. Information on product composition can be found in the safety data sheet.